KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HLTF
All Species:
14.55
Human Site:
T177
Identified Species:
24.62
UniProt:
Q14527
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14527
NP_003062.2
1009
113929
T177
K
L
G
P
A
P
K
T
L
G
F
N
L
E
S
Chimpanzee
Pan troglodytes
XP_001138277
1009
113822
T177
K
L
G
P
A
P
K
T
L
G
F
N
L
E
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534300
1106
124184
T276
K
L
G
P
A
P
K
T
L
G
F
S
L
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6PCN7
1003
113298
T177
K
L
G
P
T
P
K
T
L
G
S
S
L
E
N
Rat
Rattus norvegicus
NP_001099948
974
110023
N156
T
F
W
G
K
E
E
N
R
E
V
V
L
D
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508504
884
99044
N146
P
F
W
E
Q
R
N
N
S
Y
Y
N
T
I
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090145
999
112576
A173
G
R
A
E
N
K
Q
A
V
L
D
H
L
I
K
Zebra Danio
Brachydanio rerio
XP_693071
942
104740
F163
N
L
M
I
G
F
G
F
N
L
D
F
R
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P34739
1061
118357
G197
E
V
L
D
D
S
S
G
S
D
V
L
I
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786706
1093
121576
T223
N
L
K
S
L
D
K
T
T
E
Q
E
P
S
K
Poplar Tree
Populus trichocarpa
XP_002308876
799
88908
I61
R
C
L
Q
V
G
H
I
E
R
S
V
A
A
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FF61
881
98598
Y143
T
R
S
N
S
N
R
Y
R
I
P
C
Q
I
H
Baker's Yeast
Sacchar. cerevisiae
P31244
790
91412
E52
N
V
N
D
S
Q
D
E
E
Y
R
D
D
A
T
Red Bread Mold
Neurospora crassa
Q7S1P9
1222
137173
V233
Q
S
N
T
P
T
K
V
L
P
S
M
P
D
A
Conservation
Percent
Protein Identity:
100
99.5
N.A.
85.5
N.A.
83.6
81.4
N.A.
71.7
N.A.
64.3
53.1
N.A.
21.1
N.A.
N.A.
34.5
Protein Similarity:
100
99.8
N.A.
88
N.A.
89.7
87.9
N.A.
78.5
N.A.
79.3
69.8
N.A.
41.2
N.A.
N.A.
53.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
73.3
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
100
N.A.
100
N.A.
86.6
20
N.A.
20
N.A.
26.6
6.6
N.A.
26.6
N.A.
N.A.
20
Percent
Protein Identity:
33.6
N.A.
N.A.
36
22.7
25.2
Protein Similarity:
50.4
N.A.
N.A.
52.7
40.9
43.9
P-Site Identity:
0
N.A.
N.A.
0
0
13.3
P-Site Similarity:
6.6
N.A.
N.A.
13.3
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
22
0
0
8
0
0
0
0
8
15
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
0
15
8
8
8
0
0
8
15
8
8
15
0
% D
% Glu:
8
0
0
15
0
8
8
8
15
15
0
8
0
29
0
% E
% Phe:
0
15
0
0
0
8
0
8
0
0
22
8
0
0
0
% F
% Gly:
8
0
29
8
8
8
8
8
0
29
0
0
0
8
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
15
% H
% Ile:
0
0
0
8
0
0
0
8
0
8
0
0
8
22
0
% I
% Lys:
29
0
8
0
8
8
43
0
0
0
0
0
0
0
15
% K
% Leu:
0
43
15
0
8
0
0
0
36
15
0
8
43
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
22
0
15
8
8
8
8
15
8
0
0
22
0
0
8
% N
% Pro:
8
0
0
29
8
29
0
0
0
8
8
0
15
0
0
% P
% Gln:
8
0
0
8
8
8
8
0
0
0
8
0
8
0
0
% Q
% Arg:
8
15
0
0
0
8
8
0
15
8
8
0
8
0
0
% R
% Ser:
0
8
8
8
15
8
8
0
15
0
22
15
0
8
29
% S
% Thr:
15
0
0
8
8
8
0
36
8
0
0
0
8
0
15
% T
% Val:
0
15
0
0
8
0
0
8
8
0
15
15
0
0
8
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
15
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _